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目的比较胰岛素泵(CSII)和多次皮下注射胰岛素(MSII)治疗2型糖尿病患者高血糖的疗效。方法CSII组与MSII组患者各22例,均进行胰岛素强化治疗。治疗前CSII组空腹血糖、餐后血糖与MSII组无显著差异(P>0.05)。结果治疗后CSII组空腹血糖、3餐后2h血糖和睡前血糖均较MSII组下降显著(P<0.01),达到了预期强化控制水平。CSII组空腹血糖达标率(90.9%)显著高于MSII组(81.8%)(P<0.05),CSII组餐后血糖达标率(86.3%)显著高于MSII组(77.2%)(P<0.05)。CSII组比MSII组少用胰岛素约9.7%。结论控制血糖两种方法同样有效,但CSII组更迅速有效。
Objective To compare the effects of insulin pump (CSII) and multiple subcutaneous injections of insulin (MSII) on hyperglycemia in type 2 diabetic patients. Methods Twenty-two patients in CSII group and MSII group were given intensive insulin therapy. Before treatment, the fasting blood glucose and postprandial blood glucose in CSII group were not significantly different from those in MSII group (P> 0.05). Results After treatment, fasting blood glucose (FBG), blood glucose at 3h after meal and blood glucose before going to sleep in CSII group were significantly lower than those in MSII group (P <0.01), which reached the expected level of intensive control. The compliance rate of fasting blood glucose (90.9%) in CSII group was significantly higher than that in MSII group (81.8%) (P <0.05). The postprandial blood glucose compliance rate (86.3%) in CSII group was significantly higher than that in MSII group (77.2% . In CSII group, less insulin than MSII group was about 9.7%. Conclusion Both methods of controlling blood glucose are equally effective, but the CSII group is more rapid and effective.