论文部分内容阅读
目的探讨血清皮质醇和肌钙蛋白I(c Tn I)与急性心肌梗死(AMI)患者冠状动脉病变狭隘程度之间的关系。方法选取2014年10月至2015年10月合肥市第二人民医院收治的AMI患者60例为研究对象,同期住院但近期无心肌梗死患者30例为对照组,所有患者在院期间均行冠状动脉造影术,根据冠状动脉造影结果计算Gensini积分,比较两组皮质醇和c Tn I水平,并进行相关性分析。结果与对照组相比,患病组皮质醇[(1 333.0±146.9)nmol/L]和c Tn I[(1.06±0.039)ng/m L]升高,差异有统计学意义(P<0.05)。以全部观察对象作为整体,皮质醇与c Tn I和Gensini积分呈正相关(r=0.902、0.927,P<0.05)。结论血清皮质醇及c Tn I与急性心肌梗死患者冠状动脉病变狭隘程度相关,对AMI患者发展和预后有一定预测价值。
Objective To investigate the relationship between serum cortisol and troponin I (cTn I) and the degree of coronary artery lesion in patients with acute myocardial infarction (AMI). Methods Sixty patients with AMI who were admitted to Second People’s Hospital of Hefei from October 2014 to October 2015 were selected as the study subjects. 30 hospitalized patients without myocardial infarction in the same period were selected as the control group. All patients underwent coronary artery According to coronary angiography results, Gensini score was calculated. The levels of cortisol and cTn I in both groups were compared and the correlation analysis was performed. Results Compared with the control group, the levels of cortisol (1 333.0 ± 146.9) nmol / L and cTn I [(1.06 ± 0.039) ng / m L] were significantly increased ). Cortisol was positively correlated with cTn I and Gensini scores for all subjects (r = 0.902, 0.927, P <0.05). Conclusions Serum cortisol and cTn I are associated with the narrowing of coronary artery lesions in patients with acute myocardial infarction, which may provide some predictive value for the development and prognosis of AMI patients.