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为探讨细胞核仁组成区相关嗜银蛋白(AgNOR)在肾盂癌中的表达,对29例肾盂癌和10例正常肾盂组织标本进行了银染色。结果表明,肾盂癌AgNOR计数明显高于正常肾盂组织(P<0.01);AgNOR计数随肿瘤病理分级和分期的上升而增加。还发现肾盂癌AgNOR计数>6时,75%的患者术后可再发膀胱肿瘤。认为AgNOR颗粒数可作为鉴别良、恶性肾盂病变和评估肾盂癌生物学行为的指标之一。对肾盂癌AgNOR计数>6者,应按膀胱肿瘤对待。
To investigate the expression of AgNOR in renal pelvic carcinoma, 29 cases of renal pelvis carcinoma and 10 normal renal pelvis were stained with silver staining. The results showed that the renal pelvis cancer AgNOR count was significantly higher than normal renal pelvis (P <0.01); AgNOR count increased with the pathological grade and staging of tumors. Also found in renal pelvis cancer AgNOR count> 6, 75% of patients after recurrent bladder cancer. AgNOR particles that can be used as a differential diagnosis of benign and malignant renal pelvis lesions and evaluate the biological behavior of one of the indicators. The renal pelvis cancer AgNOR count> 6, should be treated bladder cancer.