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目的:分析尼可地尔治疗冠心病慢性心力衰竭的临床疗效。方法:将60例冠心病慢性心力衰竭患者随机分为两组,对照组30例使用常规药物进行治疗,实验组30例在常规药物治疗的基础上使用尼可地尔治疗,观察对比两组冠心病慢性心力衰竭的临床疗效。主要观察患者的脑钠肽值、左室射血分数、室间隔厚度、左室后壁厚度、左室舒张末期内径、左室收缩末期内径的变化情况。结果:与对照组比较,实验组脑钠肽值、室间隔厚度、左室后壁厚度、左室舒张末期内径、左室收缩末期内径值治疗后显著降低,左室射血分数值治疗后显著升高。两组比较差异有统计学意义(P<0.05)。结论:尼可地尔可以治疗冠心病慢性心力衰竭,并改善患者的症状和心功能。
Objective: To analyze the clinical efficacy of nicorandil in the treatment of patients with chronic heart failure of coronary heart disease. Methods: Sixty CHD patients with chronic heart failure were randomly divided into two groups. The control group, 30 cases were treated with conventional drugs. 30 cases in the experimental group were treated with Nicorandil on the basis of routine drug treatment. Chronic heart failure clinical efficacy. The main observation of patients with brain natriuretic peptide, left ventricular ejection fraction, interventricular septum thickness, left ventricular posterior wall thickness, left ventricular end-diastolic diameter, left ventricular end-systolic diameter changes. Results: Compared with the control group, the brain natriuretic peptide, the thickness of the interventricular septum, the thickness of the posterior wall of the left ventricle, the diameter of the end-diastole of the left ventricle and the diameter of the end-systolic left ventricular in the experimental group decreased significantly after treatment, and the left ventricular ejection fraction Rise. The difference between the two groups was statistically significant (P <0.05). Conclusion: Nicorandil can treat CHD with chronic heart failure and improve the symptoms and cardiac function.