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目的 探讨自由基清除剂VitC +VitE在慢性前列腺炎中的治疗作用。 方法 对117例慢性前列腺炎患者按治疗方法不同随机分为A、B、C、D四组 ,分别采用自由基清除剂、抗生素、α受体阻滞剂和安慰剂治疗。治疗前后进行前列腺按摩液 (EPS)常规检测、细菌培养 ,超氧化物歧化酶 (SOD)、丙二醛 (MDA)、最大尿流率 (Qmax)测定和IPSS评分。 结果 A组好转 18例 ,有效率47.3% ;B组好转 15例 ,有效率 46 .8% ;C组好转 2 1例 ,有效率 6 5 .6 % ;D组好转 2例 ,有效率13.3% ;A、D组比较 ,疗效明显 ,A、B、C三组间疗效差别无显著性意义。 结论 自由基清除剂可能成为治疗慢性前列腺炎的一种新方法
Objective To investigate the therapeutic effect of free radical scavenger VitC + VitE in chronic prostatitis. Methods A total of 117 patients with chronic prostatitis were randomly divided into four groups (A, B, C and D). The patients were treated with free radical scavenger, antibiotics, α-blockers and placebo respectively. Prostate massaging fluid (EPS) routine examination, bacterial culture, superoxide dismutase (SOD), malondialdehyde (MDA), maximal flow rate (Qmax) and IPSS were performed before and after treatment. Results In group A, 18 cases improved, and the effective rate was 47.3%. In group B, 15 cases were improved, with an effective rate of 46.8%. In group C, 21 cases improved, with an effective rate of 6.56%. In group D, 2 cases improved, with an effective rate of 13.3% ; A, D group, the curative effect is obvious, A, B, C difference between the three groups was not significant. Conclusion Free radical scavengers may become a new treatment for chronic prostatitis