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目的观察解毒养阴方结合IMRT治疗局部晚期鼻咽癌的临床疗效。方法将100例晚期鼻咽癌患者随机分为对照组与观察组,各50例;两组均给予全程IMRT治疗,观察组在对照组基础上给予解毒养阴方治疗,疗程8周。观察两组短期临床疗效、放疗剂量和毒副反应发生情况。结果观察组显效率为84.0%,对照组为54.0%,观察组疗效明显优于对照组(P<0.01);观察组的放疗剂量小于对照组(P<0.05);观察组毒副反应发生率为40.0%,对照组为30.0%,观察组毒副反应发生率低于对照组(P<0.05)。结论解毒养阴方结合IMRT治疗局部晚期鼻咽癌的临床疗效良好,且能减少放疗剂量,减轻毒副反应。
Objective To observe the clinical efficacy of Jiedu Yangyin Recipe combined with IMRT in the treatment of locally advanced nasopharyngeal carcinoma. Methods 100 patients with advanced nasopharyngeal carcinoma were randomly divided into control group and observation group, 50 cases in each group. Both groups were given full IMRT treatment. The observation group was given detoxification yin yin prescription on the basis of the control group for 8 weeks. Two groups of short-term clinical efficacy, radiation dose and side effects were observed. Results The effective rate was 84.0% in the observation group and 54.0% in the control group, and the therapeutic effect in the observation group was significantly better than that in the control group (P <0.01). The radiation dose in the observation group was smaller than that in the control group (P <0.05) Was 40.0% in the control group and 30.0% in the control group. The incidence of adverse reaction in the observation group was lower than that in the control group (P <0.05). Conclusion Jiedu Yangyin Fang combined with IMRT for the treatment of locally advanced nasopharyngeal carcinoma has a good clinical efficacy, and can reduce the dose of radiation and reduce side effects.