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目的探讨我院药品不良反应(ADR)发生情况,促进临床合理用药。方法对我院2010年1月至2012年5月的326例ADR报告分别从患者给药途径、药物种类以及ADR临床具体表现等方面进行回顾性统计、分析。结果 326例ADR报告结果显示,抗感染类药物引起的ADR居首位,其次是联合用药和中药。给药途径以静脉滴注方式为主,临床表现以皮肤过敏反应多见。结论应加强临床ADR报告和监测工作,合理使用抗生素,避免或减少ADR发生的关键。
Objective To investigate the incidence of adverse drug reaction (ADR) in our hospital and to promote rational drug use in clinic. Methods 326 cases of ADR from January 2010 to May 2012 in our hospital were retrospectively analyzed from the aspects of the route of administration, types of drugs and the clinical manifestations of ADR. Results 326 cases of ADR report showed that anti-infective drugs caused ADR ranks first, followed by the combination of drugs and Chinese medicine. The main route of administration by intravenous infusion, the clinical manifestations of skin allergies more common. Conclusion It is necessary to strengthen clinical ADR reporting and monitoring, rational use of antibiotics, to avoid or reduce the key to the occurrence of ADR.