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目的：为了提高严重放射性溃疡的手术疗效，争取一期愈合，防止复发。方法：采取尽量彻底清创后，以血运丰富、组织量丰厚的肌皮瓣、轴型皮瓣填充修复创面。结果：１７例中，一期愈合１３例，占７６．４７％，延期愈合４例，占２３．５３％，随访３个月至６年，无复发。结论：对于严重放射性溃疡的手术治疗，应尽量彻底清创后，采用血运丰富的皮瓣或肌皮瓣修复创面，同时皮瓣或肌皮瓣的组织量要丰厚，充分填充创面，不留死腔，是争取一期愈合的关键。
Objective: In order to improve the surgical efficacy of severe radiation ulcers, for a healing, to prevent recurrence. Methods: After thorough debridement as much as possible, the myofascial flap and axial skin flap with abundant blood supply and abundant tissue volume were used to fill the wound. Results: In the 17 cases, 13 cases (76.47%) were healed in the first phase, 4 cases delayed healing (23.53%), followed up for 3 months to 6 years without recurrence. Conclusion: For the surgical treatment of severe radioactive ulcer, as far as possible after thorough debridement, the wounds should be repaired by blood-rich flaps or myocutaneous flaps. At the same time, the flap or myocutaneous flap should be rich in tissue volume to fully fill the wound without leaving Dead space, is the key to a period of healing.