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目的探索少量饮酒与女性乳腺癌的关系。方法计算机检索中国知网数据库(CNKI),重庆维普中文科技期刊数据库(VIP),万方数据库等中文数据库和Pub Med,Pro Quest,Cochrane Library等英文数据库,收集国内外截止到2016年1月1日发表的关于少量饮酒与女性乳腺癌关系的队列研究文献。应用Stata12软件进行Meta分析。结果共纳入合格文献17篇,少量饮酒与女性乳腺癌发病关系的合并RR值为1.073(95%CI 1.022~1.127;I2=58.7%,P=0.001;n=17)。Egger’s检验P=0.208,同时Begg’s检验P=0.232,所分析的文献无显著的发表偏倚存在。结论少量饮酒可增加女性乳腺癌发病风险。
Objective To explore the relationship between a small amount of alcohol consumption and female breast cancer. Methods The Chinese databases such as CNKI, VIP, Chongqing Library, Wanfang Database, PubMed, Pro Quest and Cochrane Library were searched by computer. The data collected at home and abroad as of January 1, 2016 Published in a small amount of alcohol on the relationship between women and breast cancer research cohort literature. Meta-analysis was performed using Stata12 software. Results A total of 17 articles were included in the literature. The pooled RR of the association between a small amount of drinking and breast cancer was 1.073 (95% CI 1.022-1.127; I2 = 58.7%, P = 0.001; n = 17). Egger’s test P = 0.208, and Begg’s test P = 0.232, there was no significant publication bias in the analyzed literature. Conclusion Small amount of alcohol can increase the risk of breast cancer in women.