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阿司匹林是临床上疗效可靠的常用药物。因有些药物和其他药物合用时可产生协同作用可能有益,但也有害者,影响药物疗效及不良反应。因此,使用阿司匹林(包括A.P.C)时,应别特注意。阿司匹林+保泰松、消炎痛、含醇饮料:阿司匹林具有较强的刺激性,有引起消化道溃疡和隐性出血的可能性;保泰松、消炎痛及含醇饮料等也能刺激胃粘膜,促使溃疡的形成。当它们合用时,致溃疡作用增强。阿司匹林能将其乙酰基移换给白蛋白,从而增加其结合保泰松的能力,影响保泰松的作用。阿司匹林也能使消炎痛的作用减弱。阿司匹林+口服降血糖药:应用磺酰脲类
Aspirin is clinically effective and commonly used drugs. Because some drugs and other drugs can produce synergy when combined may be beneficial, but also harmful, affecting drug efficacy and adverse reactions. Therefore, special attention should be paid when using aspirin (including A.P.C). Aspirin + phenylbutazone, indomethacin, alcoholic beverages: Aspirin has a strong irritant, causing gastrointestinal ulcers and the possibility of occult bleeding; phenylbutazone, indomethacin and alcoholic beverages can also stimulate the gastric mucosa , To promote the formation of ulcers. When they are combined, the ulcer effect increases. Aspirin can shift its acetyl group to albumin, thereby increasing its ability to bind phenylbutazone, affecting the effects of phenylbutazone. Aspirin can also reduce the role of indomethacin. Aspirin + Oral Hypoglycemic Drugs: Use Sulfonylureas