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本研究目的在于分析卵巢癌腹水和血清CA125水平,以及与临床状况、预后和腹腔细胞学之间的关系。从1983年6月至1987年10月,用剖腹探查术和腹腔穿刺术共取得70例卵巢癌和32例对照者未稀释的腹水标本。全部病例均随访至1991年1月,随访期39～89个月(平均随访56个月),无失访者。临床分期采用FIGO规定的分期法,其中包括卵巢癌Ⅰ期患者20例,Ⅱ期5例,Ⅲ期32例和Ⅳ期13例。组织学分类采用WHO标准。浆液性囊腺癌35例,粘液性囊腺癌10例,子宫内膜样腺癌6例,透明细胞癌5例,未分化癌8例和混合性上皮癌6例。所有复发者均经组织学或细胞学证实。对照者32例,18例是行输卵管绝育术的健康妇女,15例为
The aim of this study was to analyze the levels of ascites and serum CA125 in ovarian cancer, as well as the relationship with clinical status, prognosis and celiac cytology. From June 1983 to October 1987, 70 patients with ovarian cancer and 32 controls with undiluted ascites were obtained by laparotomy and peritoneal puncture. All cases were followed up until January 1991. The follow-up period was 39 to 89 months (mean follow-up of 56 months). No patients were lost to follow-up. The staging of FIGO was used for clinical staging, including 20 cases of stage I ovarian cancer, 5 cases of stage II, 32 cases of stage III, and 13 cases of stage IV. The histological classification uses the WHO standard. There were 35 cases of serous cystadenocarcinoma, 10 cases of mucinous cystadenocarcinoma, 6 cases of endometrioid adenocarcinoma, 5 cases of clear cell carcinoma, 8 cases of undifferentiated carcinoma and 6 cases of mixed epithelial carcinoma. All recurrences were confirmed by histology or cytology. Thirty-two controls, 18 cases of healthy women undergoing tubal sterilization, 15 cases