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目的：探讨中晚期食管癌病人化疗疗程效应与远期生存的关系。方法：对４１例病人不同的疗程化疗效应，应用Ｃｐｄ分析方法，做了数理分析，同时统计了远期生存，结果：随着化疗疗程的增加，实体瘤近期疗效降低，在Ｐ＜０．０５意义下，第Ⅰ疗程最好，第Ⅲ疗程最差，第Ⅱ疗程居中；中位生存期分别为：完成３个疗程的病人９．０个月，１～２个疗程为８．３个月，Ｘ２＝０．６４２，Ｐ＞０．０５。结论：从生存质量和远期生存考虑Ⅱ～Ⅲ期食管癌病人化疗的选择，以两个疗程为好。
Objective: To investigate the relationship between the effect of chemotherapy and long-term survival in patients with advanced esophageal cancer. Methods: The effect of different courses of chemotherapy on 41 patients was analyzed by Cpd analysis method. The long-term survival was also calculated. Results: With the increase of chemotherapy course, the curative effect of solid tumor was reduced, P<0.05 In the sense, the first course was the best, the third stage was the worst, and the second stage was middle; the median survival period was: 9.0 months for patients who completed 3 courses, and 8.3 months for 1-2 courses. X2=0.642, P>0.05. Conclusion: Considering the choice of chemotherapy for patients with esophageal cancer in stage II-III from the quality of life and long-term survival, it is better to use two courses.