论文部分内容阅读
目的研究集束化治疗依从率对脓毒血症休克患者的疗效及预后情况,为临床治疗提供参考依据。方法分析2013年1月-2014年6月于医院接受治疗的78例脓毒血症休克患者的临床资料,将42例接受集束化治疗的患者列为观察组,把36例采用常规治疗的脓毒血症休克患者纳为对照组;观察两组患者依从性和相关预后指标。结果 78例脓毒血症休克患者感染病原菌主要以革兰阴性菌感染为主,占70.51%;观察组患者6h、24h时的平均动脉压(MAP)、中心静脉压(CVP)、中心静脉血氧饱和度(ScvO_2)、动脉血乳酸水平高于对照组,差异有统计学意义(P<0.05);治疗后,观察组患者的住院时间、急性生理与慢性健康(APACHE Ⅱ)评分、序贯器官衰竭估计(SOFA)评分显著低于对照组,差异有统计学意义(P<0.05);集束化治疗依从组患者的28d生存率显著高于常规治疗依从组患者,差异有统计学意义(P<0.05)。结论提高医务人员对于脓毒血症休克治疗的依从性可以有效改善患者血液循环功能,降低患者的病死率,对于脓毒血症休克早期的治疗具有良好的临床实用价值。
Objective To study the curative effect and prognosis of cluster therapy compliance on septic shock patients and provide reference for clinical treatment. Methods Clinical data of 78 septic shock patients admitted to the hospital from January 2013 to June 2014 were analyzed. Twenty-four patients undergoing cluster therapy were enrolled in the observation group. Thirty-six patients with conventional treatment of pus Patients with sequelae of shock as a control group; observed two groups of patients compliance and related prognostic indicators. Results The main pathogenic bacteria in 78 patients with sepsis shock were gram-negative bacteria, accounting for 70.51%. Mean arterial pressure (MAP), central venous pressure (CVP), central venous pressure Oxygen saturation (ScvO_2), arterial blood lactate levels were higher than the control group, the difference was statistically significant (P <0.05); After treatment, the observation group patients’ hospital stay, acute physiology and chronic health (APACHE Ⅱ) score, The organ failure assessment (SOFA) score was significantly lower than that of the control group (P <0.05), and the 28-day survival rate was significantly higher in the patients receiving the intensive treatment group than in the conventional treatment-compliance group (P <0.05). Conclusions Increasing the compliance of medical staff for the treatment of septic shock can effectively improve the circulatory function of patients and reduce the mortality of patients, which has a good clinical value for early treatment of septic shock.