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目的:探讨完全电视辅助胸腔镜手术(CVATS)与开胸手术比较治疗非小细胞肺癌的安全性及有效性。方法:选择近3年内单一手术组连续实施肺叶或全肺切除术治疗非小细胞肺癌患者共111例,按照手术方式分为CVATS组52例,开胸组59例。比较两组手术时间、术后并发症及生存率等情况。结果:两组患者在年龄、肿瘤类型及术后分期上无差异,CVATS组女性患者多于开胸组(40.4%vs 22.0%,P=0.036)。两组在手术时间、术后并发症的发生率、无瘤生存率及总体生存率上均无差异,CVATS组术后住院天数较开胸组短(10.6±3.8 vs 12.6±5.7,P=0.013)。结论:与开胸手术相比,CVATS治疗肺癌同样安全且具有术后恢复快的优势,近期疗效可靠。
Objective: To investigate the safety and efficacy of complete video-assisted thoracoscopic surgery (CVATS) versus thoracotomy in the treatment of non-small cell lung cancer. Methods: A total of 111 patients with non-small cell lung cancer who underwent continuous lobectomy or pneumonectomy in a single operation group in the last 3 years were divided into CVATS group (n = 52) and thoracotomy group (n = 59) according to the operation method. The operation time, postoperative complications and survival rate were compared between the two groups. Results: There was no difference in age, tumor type and postoperative staging between the two groups. There were more female patients in the CVATS group than in the thoracotomy group (40.4% vs 22.0%, P = 0.036). There was no difference in operative time, incidence of postoperative complications, tumor-free survival and overall survival between the two groups. The postoperative days of hospital stay in CVATS group were shorter than those in open thoracotomy group (10.6 ± 3.8 vs 12.6 ± 5.7, P = 0.013 ). Conclusions: Compared with thoracotomy, CVATS is equally safe and has the advantage of rapid postoperative recovery. It is reliable in the near future.