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目的了解功能性肠病的临床症状特点。方法对2005年8月至2006年5月门诊行结肠镜检查的所有患者进行连续闾卷调查,按照罗马Ⅱ标准诊断功能性肠病,以器质性肠病作为对照,分析研究功能性肠病的临床特点。结果共有1820人参加调查。功能性肠病患者较之器质性患者,女性所占比例为大(51.79%比48.21%,P<0.05),前者发病年龄较后者为轻,[(41.30±0.39)岁比(66.28±0.51)岁.P<0.05]。年龄大于40岁的患者中功能性肠病所占比例随年龄增加逐渐降低,而器质性肠病所占比例逐渐升高。年龄大于60岁的患者中,器质性肠病所占比例超过功能性肠病。功能性肠病较之器质性肠病者的腹痛、腹胀、腹部不适、腹泻、便秘、大便不尽感发生率高(P值均<0.05),腹泻便秘交替、肛门坠胀感、大便窘迫感及手辅助排便等症状在功能性及器质性肠病中的发生率差异均无统计学意义(P值均>0.05)。功能性肠病伴上消化道症状的发生率较之器质性肠病明显增高(P<0.05)。功能性较之器质性肠病上腹痛、上腹胀、恶心、食欲下降、早饱、反酸、反流、烧心发生率为高(P值均<0.05),上腹不适和呕吐在功能性及器质性肠病患者中的发生率差异无统计学意义(P值均>0.05)。结论功能性肠病与器质性肠病患者的发病年龄、性别、症状等有明显差异,临床上进行较为细致的分析将有助于初步鉴别。
Objective To understand the clinical features of functional bowel disease. Methods From August 2005 to May 2006, all patients undergoing colonoscopy were surveyed continuously. According to the Rome II standard, functional bowel disease was diagnosed, and organic bowel disease was used as a control to analyze and study the functional bowel disease The clinical features. A total of 1820 people participated in the survey. The proportion of women with functional bowel disease was significantly higher than that of organic ones (51.79% vs. 48.21%, P <0.05), while the former was lighter than the latter (41.30 ± 0.39 vs 66.28 ± 0.51) years old. P <0.05]. The proportion of functional bowel disease in patients older than 40 years old gradually decreased with age, while the proportion of organic bowel disease gradually increased. Among patients older than 60 years old, organic enteropathy accounts for more than functional bowel disease. Functional bowel disease than those with organic intestinal disease abdominal pain, abdominal distension, abdominal discomfort, diarrhea, constipation, high incidence of stool (P <0.05), alternating diarrhea, constipation, anus bulge, stool distress There was no significant difference in the incidence of functional and organic bowel disease among the symptoms such as hand feeling and hand defecation (P> 0.05). The incidence of functional bowel disease with upper gastrointestinal symptoms was significantly higher than that of organic intestinal disease (P <0.05). Function than the organic bowel disease on the abdominal pain, abdominal distension, nausea, loss of appetite, early satiety, acid reflux, heartburn (P <0.05), upper abdominal discomfort and vomiting in the functional And organic enteropathy in patients with no significant difference (P> 0.05). Conclusion There is a significant difference in the age, sex and symptoms of patients with functional bowel disease and organic intestinal disease. A more detailed analysis in clinical practice will be helpful for the preliminary identification.