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为了明确雄性激素和骨髓移植在治疗严重再生障碍性贫血的作用,作者于1974年1月开始进行预期的随机研究。本文报告110例严重再障治疗结果。严重再障的定义:①骨髓细胞量低于正常的25%或骨髓细胞量低于正常的50%及造血细胞低于30%;②周围血细胞计数至少具有下列3项中的2项:粒细胞低于500/mm~3;血小板低于20,000/mm~3,贫血及网织红细胞低于1%(根据红细胞压积校正的)。
In order to clarify the role of androgen and bone marrow transplantation in the treatment of severe aplastic anemia, the authors began the expected randomized study in January 1974. This article reports 110 cases of severe aplastic anemia treatment results. Definition of severe aplastic anemia: ① bone marrow cells below normal 25% or myeloid cells below 50% of normal and less than 30% of hematopoietic cells; ② peripheral blood cell count with at least two of the following three: granulocyte Less than 500 / mm ~ 3; platelets less than 20,000 / mm ~ 3, anemia and reticulocytes less than 1% (corrected for hematocrit).