患者女 ,42岁。因左乳肿物 8个月 ,于 2 0 0 0年 8月 16日入院。患者无吸烟等不良嗜好 ,无肿瘤家族史。查体 :左乳头内陷 ,乳晕周围皮肤橘皮样改变 ,乳晕下方可触及 10ｃｍ×12ｃｍ肿物 ,质地硬 ,活动。左腋窝可触及肿大融合淋巴结 ,左锁骨上和左颈部亦可扪及肿大淋巴结。左侧 Female patient, 42 years old. Due to left breast mass for 8 months, she was admitted to hospital on August 16, 2000. The patient had no bad habits such as smoking and no family history of cancer. Physical examination: Invagination of the left nipple, skin orange peel around the areola changes, 10cm × 12cm mass can be touched below the areola, hard texture, activity. The left axillary fossa can touch the enlarged fusion lymph nodes, and the left supraclavicular and left neck can also be swollen and enlarged lymph nodes. Left side