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[目的]观察参麦注射液、红花注射液联合西药治疗慢性肺源性心脏病的临床疗效。[方法]选择80例慢性肺源性心脏病患者分为两组,对照组40例采用常规西医治疗,治疗组40例在对照组治疗基础上同时给予参麦注射液60mL/d、红花注射液20mL/d稀释静脉点滴。观察血流动力学指标、血液流变学指标、动脉血气指标及临床症状改善。两组均以2周为1个疗程,治疗1个疗程后判定疗效。[结果]血流动力学各项指标治疗组均有明显改善,对照组改善不明显。血液流变学各项指标治疗组均有明显改善,对照组改善不明显。动脉血气指标治疗组治疗后动脉血二氧化碳分压下降,氧分压比治疗前升高,对照组改善不明显。临床疗效治疗组优于对照组。[结论]参麦注射液联合红花注射液治疗慢性肺源性心脏病有纠正心力衰竭和改善血液黏滞度,降低肺动脉高压,改善肺心病呼吸功能的作用。
[Objective] To observe the clinical effects of Shenmai injection, safflower injection and western medicine in the treatment of chronic cor pulmonale. [Method] Eighty patients with chronic cor pulmonale were divided into two groups. The control group was treated with routine Western medicine. The treatment group was given 40 mg Shenmai injection on the basis of the control group, Liquid 20mL / d diluted intravenous drip. Hemodynamics, hemorheology, arterial blood gas and clinical symptoms were observed. Two groups were 2 weeks for a course of treatment, treatment of a course of treatment to determine the efficacy. [Results] The indexes of hemodynamics treatment group were significantly improved, but the improvement of control group was not obvious. Hemorheology indicators of the treatment group were significantly improved, the control group improved not obvious. Arterial blood gas index after treatment, arterial partial pressure of carbon dioxide decreased oxygen partial pressure than before treatment increased, the control group did not improve significantly. Clinical efficacy of treatment group than the control group. [Conclusion] Shenmai injection combined with safflower injection in the treatment of chronic cor pulmonale has the effect of correcting heart failure, improving blood viscosity, reducing pulmonary hypertension, and improving respiratory function of pulmonary heart disease.