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目的 评价金属内支架置入并放化疗治疗食管癌的临床效果。材料与方法 放化疗组 3 5例中 ,男 19例 ,女 16例。年龄45～ 76岁 ,平均 66岁。病程 1～ 16个月 ,平均 6个月。全部病例经食管镜或病理确诊为食管癌并置入内支架后行放化疗。 3 1例放疗 ,剂量DT60～ 70Gy/6～ 7周 ,4例经胃左动脉灌注顺铂 2 0 0mg ,阿霉素 60～ 70mg ,5 氟尿嘧啶 10 0mg。对照组 3 5例中 ,男 2 1例 ,女 14例。年龄 45～ 75岁。病程 1～ 18个月 ,平均 6.5个月。结果 食管癌置入内支架放化疗随访观察 ,食管内支架通畅时间 1～ 5年者占 2 0 % ,再狭窄率为 48% ,比未放化疗食管癌置入支架组通畅时间长 ,再发狭窄率低。结论 中晚期食管癌置入内支架后进行放化疗能有效地防止再狭窄 ,延长生存时间
Objective To evaluate the clinical effect of stenting and chemoradiotherapy in the treatment of esophageal cancer. Materials and Methods Radiotherapy and chemotherapy group of 35 patients, 19 males and 16 females. Age 45 to 76 years, average 66 years old. Duration of 1 to 16 months, an average of 6 months. All cases were diagnosed as esophageal cancer by esophagoscopy or pathology and placed in stents before radiotherapy and chemotherapy. In 31 cases of radiation therapy, the dose of DT60 ~ 70Gy/6 ~ 7 weeks, 4 cases of transgastric artery perfusion of cisplatin 200mg, doxorubicin 60 ~ 70mg, 5 fluorouracil 100mg. In the control group of 35 patients, there were 21 males and 14 females. Age 45 to 75 years old. Duration of 1 to 18 months, an average of 6.5 months. RESULTS: Esophageal carcinoma was followed up by internal stenting and radiotherapy and chemotherapy. The patency time of esophageal stents was 1 to 5 years, accounting for 20%, and the restenosis rate was 48%. This was longer than that of ungrafted esophageal carcinoma stents. Stenosis rate is low. Conclusion Radiotherapy and chemotherapy after stent placement in advanced esophageal cancer can effectively prevent restenosis and prolong survival time.