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目的:观察肝复乐胶囊加常规治疗乙型肝炎肝硬化的效果。方法:选择乙型肝炎肝硬化95例,随机分为观察组49例和对照组46例。对照组采用常规治疗,观察组在对照组治疗基础上加用肝复乐胶囊。比较两组治疗后血清丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、甲胎蛋白(AFP)、血清清蛋白(ALB)的改善率,门静脉宽度及脾厚度变化情况。结果:观察组ALT、AST及AFP改善率显著高于对照组(P<0.05),ALB改善率两组差异不显著(P>0.05)。对照组门静脉宽度、脾厚度治疗前后差异不显著(P>0.05);观察组门静脉宽度、脾厚度治疗后显著小于治疗前(P<0.05),脾厚度又显著小于对照组治疗后(P<0.05)。结论:肝复乐胶囊加常规治疗乙型肝炎肝硬化的效果优于常规治疗。
Objective: To observe the effect of Ganfural capsule plus conventional treatment of hepatitis B cirrhosis. Methods: 95 cases of hepatitis B cirrhosis were randomly divided into observation group (49 cases) and control group (46 cases). The control group with conventional treatment, the observation group in the control group based on the use of liver rehabilitation capsules. The changes of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), AFP, ALB, portal vein width and spleen thickness were compared between the two groups Happening. Results: The improvement rates of ALT, AST and AFP in the observation group were significantly higher than those in the control group (P <0.05). There was no significant difference in the improvement rate of ALB between the two groups (P> 0.05). The portal vein width and spleen thickness in the control group were significantly lower than those before treatment (P <0.05), and the spleen thickness was significantly smaller than that in the control group after treatment (P <0.05) ). Conclusion: Ganfural capsules plus conventional treatment of hepatitis B cirrhosis better than conventional treatment.