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目的观察上下关节腔联合注射透明质酸治疗颞下颌关节紊乱的临床效果。方法将颞下颌关节紊乱患者212例随机分为试验组和对照组各106例。试验组于上下关节腔联合注射透明质酸治疗,对照组仅单纯关节上腔注射。评价2组VAS评分、Helkimo临床功能障碍指数和最大张口指数。治疗有效率根据患者临床症状改善程度、颞下颌关节功能及治疗并发症综合评估。结果治疗前2组患者VAS评分、Helkimo指数和最大张口指数均相近,差异均无统计学意义(P>0.05)。治疗后2组患者VAS评分和Helkimo指数均降低,最大张口指数均升高,且试验组变化幅度大于对照组;试验组治疗后总有效率高于对照组,差异均有统计学意义(P<0.05)。2组患者治疗后并发症发生率相近差异无统计学意义(P>0.05)。结论上下关节腔联合注射透明质酸治疗颞下颌关节紊乱具有良好的治疗效果。
Objective To observe the clinical effect of joint injection of hyaluronic acid into the upper and lower articular cavities on temporomandibular joint disorders. Methods 212 patients with temporomandibular disorder were randomly divided into test group and control group, with 106 cases each. The experimental group was treated with combined hyaluronic acid injection in the upper and lower articular cavities, while the control group was injected with only the superior articular cavity. Group 2 VAS score, Helkimo clinical dysfunction index and maximum mouth opening index. The effectiveness of treatment based on the degree of improvement of clinical symptoms, temporomandibular joint function and treatment of complications in a comprehensive assessment. Results Before treatment, the VAS score, Helkimo index and maximum mouth opening index of two groups were similar, the difference was not statistically significant (P> 0.05). After treatment, the VAS score and Helkimo index of the two groups were decreased, the maximum mouth index was increased, and the change range of the experimental group was greater than that of the control group. The total effective rate of the experimental group after treatment was significantly higher than that of the control group (P < 0.05). There was no significant difference in the incidence of complications between the two groups (P> 0.05). Conclusion The combination of upper and lower articular cavities with hyaluronic acid has a good therapeutic effect on temporomandibular joint disorders.