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目的:比较肺炎支原体感染或细菌感染患儿的血常规及C反应蛋白(CRP)的变化规律。方法:肺炎支原体感染(支原体感染组)与细菌感染(细菌感染组)患儿各80例,80例正常儿童作为对照组,检测入院或体检时3组儿童血红蛋白(Hb)含量、白细胞(WBC)和红细胞(RBC)及血小板(PLT)计数,中性粒细胞、淋巴细胞及单核细胞分类;采用酶联免疫法(ELISA)法测定3组儿童血清中C反应蛋白(CRP)水平。结果:3组儿童RBC及PLT计数比较,差异无统计学意义(P>0.05);与对照组比较,细菌感染组和支原体感染组WBC计数、中性粒细胞和单核细胞分类及血清CRP水平升高,淋巴细胞分类降低,而Hb含量仅支原体感染组降低,单核细胞分类仅支原体感染组升高,差异有统计学意义(P<0.05);与细菌感染组比较,支原体感染组患儿WBC计数、Hb含量及CRP水平降低,而单核细胞分类升高,差异有统计学意义(P<0.05)。结论:临床可根据WBC计数、单核细胞分类、Hb含量及CRP水平辅助鉴别诊断儿童肺炎支原体感染及细菌感染。
Objective: To compare the changes of blood routine and C-reactive protein (CRP) in children with Mycoplasma pneumoniae infection or bacterial infection. Methods: Eighty children with mycoplasma pneumoniae infection (mycoplasma infection group) and bacterial infection (bacterial infection group) and 80 normal children served as the control group. The levels of hemoglobin (Hb), white blood cell (WBC) (RBC) and platelet count (PLT), neutrophils, lymphocytes and monocytes. Serum C-reactive protein (CRP) levels were measured by enzyme-linked immunosorbent assay (ELISA) Results: There were no significant differences in RBC and PLT count between the three groups (P> 0.05). Compared with the control group, the WBC count, neutrophil and monocyte classification and serum CRP level in bacterial infection group and mycoplasma infection group (P <0.05). Compared with the bacterial infection group, the infection rate of mycoplasma infection group was significantly higher than that of the control group WBC count, Hb content and CRP levels decreased, while monocyte classification increased, the difference was statistically significant (P <0.05). Conclusion: According to WBC count, monocyte classification, Hb content and CRP level, the clinical diagnosis of Mycoplasma pneumoniae infection and bacterial infection can be assisted.