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目的分析药敏试验对抗菌药物合理用药的重要意义。方法选取2013年6月-2016年6月医院经验性使用抗菌药物的患者1 136例进行回顾性分析,根据是否进行药敏试验分为观察组和对照组各568例,对比2组患者的治疗有效率以及使用抗菌药物的不良反应发生率。结果观察组患者治疗总有效率为99.12%,高于对照组的89.61%,差异有统计学意义(P<0.05)。观察组患者使用抗菌药物发生发热、白细胞增多、切口感染的发生率均低于对照组,差异均有统计学意义(P<0.05)。结论对使用抗菌药物的患者予以药敏试验,并根据试验结果进行合理干预,能够提高患者的临床治疗效果,并有效降低不良反应的发生率,有利于患者尽快恢复健康,具有临床推广价值。
Objective To analyze the importance of drug susceptibility testing for rational use of antimicrobial agents. Methods A retrospective analysis was performed on 1 136 cases of patients with empirical antibiotics in our hospital from June 2013 to June 2016. 568 patients in observation group and control group were divided according to whether drug sensitivity test was conducted or not, Efficacy and incidence of adverse reactions using antibiotics. Results The total effective rate of observation group was 99.12%, which was higher than 89.61% of control group, the difference was statistically significant (P <0.05). The incidence of fever, leukocytosis and incision infection in the observation group was lower than that in the control group, with significant difference (P <0.05). Conclusion Susceptibility testing of patients receiving antimicrobial agents and rational intervention according to the test results can improve the clinical efficacy of patients and reduce the incidence of adverse reactions, which is beneficial to the patients recovering their health as soon as possible and has clinical promotion value.