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目的评估天津市乙型肝炎(乙肝)相关肝硬化、肝癌死亡潜在寿命损失。方法按死亡时间对2013年自《人口死亡信息登记管理系统》导出的根本死因中肝硬化、肝癌死亡数据进行排序,通过系统抽样抽取死者名单,通过家属和医院调查确认其死亡根本原因与乙肝病毒(HBV)慢性感染的关联,然后计算乙肝相关死亡潜在寿命损失等。结果抽取的770例死者中经核查后与乙肝相关的有391例,潜在减寿年数(PLYY)6167a,主要发生在40~59岁(4 299 a),其中肝硬化潜在减寿年数均值(ALYY)(19±12)岁,高于肝癌的(16±11)岁(Z=2.140,P=0.032)。男性PLYY为5002a,ALYY为(18±11)岁,推算减寿率(YPLLR)为1.73‰,分别高于女性的1165a,(14±12)岁(Z=2.315,P=0.021)和0.58‰(χ~2=3906.967,P=0.000)。结论天津中年男性人群乙肝导致的相关肝硬化和肝癌死亡的潜在寿命损失仍较大,应完善死因登记中乙肝等传染病相关死亡登记。
Objective To assess the potential loss of life-long death from hepatitis B (hepatitis B) -related liver cirrhosis and liver cancer in Tianjin. Methods According to the time of death, the data of death from liver cirrhosis and liver cancer from the “cause of death registration system” in 2013 were sorted according to the time of death, and the list of deceased persons was sampled by systematic sampling. The causes of death were confirmed by family and hospital surveys and hepatitis B virus (HBV) chronic infection, and then calculate the potential loss of life expectancy related to HBV-related death. Results Among 770 deceased persons, there were 391 cases of HBV-related deaths with a PLTY of 6167a, mainly occurring between 40 and 59 years old (4 299 years), of which the average number of potential years of longevity of liver cirrhosis (ALYY ) (19 ± 12) years old and (16 ± 11) years older than liver cancer (Z = 2.140, P = 0.032). The male PLYY was 5002a, the ALYY was (18 ± 11) years old, and the projected loss of life (YPLLR) was 1.73 ‰, which were higher than those of women 1165a, (14 ± 12) years (Z = 2.315, P = 0.021) (χ ~ 2 = 3906.967, P = 0.000). Conclusion The potential loss of life-related death from liver cirrhosis and liver cancer caused by hepatitis B in middle-aged male population in Tianjin is still large, and registration of related deaths such as hepatitis B in the cause of death registration should be improved.