论文部分内容阅读
作者对部分成员已被证实患有甲状腺髓样癌的一个大家族应用血清降钙素测定进行筛选。89个成员中,12人血清及尿中降钙素水平增高,其中11人缺乏甲状腺癌的症状或体征。所有12人均进行全甲状腺切除术。每例均发现双侧甲状腺髓样癌。肿瘤大小从镜下可见至1.4毫米直径。5例肿瘤局限于甲状腺,7例有颈局部淋巴结转移。术前仅1例应用放射性
The authors screened a large family of people whose members have been diagnosed with medullary thyroid carcinoma using a serum calcitonin assay. Of the 89 members, 12 had elevated serum and urinary calcitonin levels, and 11 of them lacked the symptoms or signs of thyroid cancer. All 12 patients underwent total thyroidectomy. Bilateral thyroid medullary carcinoma was found in each case. Tumor size can be seen from the microscope to 1.4 mm in diameter. 5 cases of tumor confined to the thyroid gland, 7 cases of cervical lymph node metastasis. Only 1 case applied radioactivity before surgery