目的 :探讨巯甲丙脯酸致咳嗽的规律 ,为临床用药提供依据。方法 :对1998年1月～1999年6月我院用疏甲丙脯酸的患者进行统计 ,并对致咳嗽的病例进行分析。结果 :巯甲丙脯酸致咳嗽的发生率为4 03 % ,女性的发生率明显高于男性 ,与用药量、年龄、原发病的关系很小 ,无显著差异。结论 :巯甲丙脯酸致咳常易被误诊 ,在临床应用中要高度警惕其副作用 Objective: To investigate the rule of captopril induced cough and provide basis for clinical medication. Methods: From January 1998 to June 1999, the patients in our hospital were surveyed with captopril, and the cases of cough were analyzed. Results: The incidence of cough caused by captopril was 403%. The incidence of cough in women was significantly higher than that in men. There was no significant difference between drug consumption, age and primary disease. Conclusion: Captopril induced cough often misdiagnosed, in clinical application should be highly vigilant its side effects