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目的:探讨2013年1月—2014年12月门诊口服降糖药物的临床应用现状。方法:收集门诊2013年1月—2014年12月期间口服降糖药处方5 120张,其中4 352张符合纳入要求。采用限定日剂量分析法对该类药物使用进行用药频度(DDDs)分析。结果:二甲双胍连续两年DDDs排序第1位,阿卡波糖DDDs值及排序均有明显增长,吡格列酮连续两年DDDs排序第3位。结论:该院口服降糖药物的应用基本合理,二甲双胍使用频率高,符合安全、有效、经济的用药原则。
Objective: To investigate the clinical application of oral glucose-lowering drugs in clinic from January 2013 to December 2014. Methods: 5 120 oral hypoglycemic agents were collected during the period from January 2013 to December 2014 in Outpatient Department, of which 4 352 cases met the inclusion criteria. Drug use frequency (DDDs) analysis of the use of such drugs was conducted using a defined daily dose analysis. RESULTS: Metformin was ranked first in DDDs for two consecutive years. DDDs values and rankings in acarbose were significantly increased. Pioglitazone ranked the third in DDDs for two consecutive years. Conclusion: The oral administration of oral hypoglycemic drugs in the hospital is reasonable and rational. Metformin is used frequently, which is in line with the safe, effective and economical medication principle.