论文部分内容阅读
目的:探究甘精胰岛素联合二甲双胍和单一药物在糖尿病患者中的疗效。方法:研究对象为78例糖尿病患者,按随机原则将其分为对照组(39例)和观察组(39例)。对照组采用单一药物(即二甲双胍)治疗,观察组则采用甘精胰岛素联合二甲双胍进行治疗,观察两组患者的血糖达标时间、治疗后空腹和餐后两小时的血糖水平以及不良反应的发生情况。结果:观察组的血糖达标时间短于对照组,空腹与餐后两小时的血糖水平均低于对照组,不良反应发生率也低于对照组,且差异具有统计学意义(P<0.05)。结论:采用甘精胰岛素联合二甲双胍治疗糖尿病患者可有效缩短其血糖达标时间,降低其血糖水平,值得临床推广。
Objective: To investigate the efficacy of insulin glargine combined with metformin and single drug in patients with diabetes mellitus. Methods: A total of 78 patients with diabetes mellitus were randomly divided into control group (39 cases) and observation group (39 cases). The control group was treated with a single drug (metformin). The observation group was treated with insulin glargine and metformin. The time of reaching the blood glucose level, the fasting and postprandial two hours blood glucose level and the incidence of adverse reactions were observed in two groups. Results: The blood glucose of observation group was shorter than the control group, the fasting and postprandial blood glucose levels were lower than the control group, the incidence of adverse reactions is also lower than the control group, and the difference was statistically significant (P <0.05). Conclusion: Glargine and metformin in diabetic patients can effectively shorten the time of its blood glucose and lower its blood glucose level, which deserves clinical promotion.