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目的分析降钙素原(PCT)定量检测在细菌感染中的临床应用价值。方法回顾性分析2013年2月—2014年2月长葛市人民医院收治的108例感染性疾病患者的临床资料,按照疾病类型分为两组,52例非脓毒性疾病患者为对照组,56例脓毒性疾病患者为研究组,两组患者均采用免疫荧光定量检测法(ELFA)检查的血浆PCT水平,并比较不同临床结果患者的PCT水平,评价PCT与预后的关系。结果研究组患者的PCT阳性率高于对照组,差异有统计学意义(P<0.05)。存活组血浆患者PCT水平为(14.2±8.8)ng/ml,低于死亡患者的(56.8±20.7)ng/ml,差异有统计学意义(P<0.05)。结论 PCT定量检测可直接用于临床细菌感染诊断过程中,有效提示患者的细菌感染情况,且可根据PCT值直接评估患者的病情及预后效果。
Objective To analyze the clinical value of procalcitonin (PCT) quantitative detection in bacterial infection. Methods The clinical data of 108 cases of infectious diseases admitted to Changge Municipal People’s Hospital from February 2013 to February 2014 were retrospectively analyzed. According to the type of disease, 52 cases were divided into two groups. Fifty-two patients with non-septic disease as control group. 56 The patients with sepsis were selected as study group. Plasma PCT levels were detected by immunofluorescence assay (ELFA) in both groups. PCT levels in patients with different clinical outcomes were compared to evaluate the relationship between PCT and prognosis. Results The positive rate of PCT in study group was higher than that in control group (P <0.05). The level of PCT in the survivors plasma was (14.2 ± 8.8) ng / ml, which was lower than that of the dead patients (56.8 ± 20.7) ng / ml, the difference was statistically significant (P <0.05). Conclusion PCT quantitative test can be directly used in the diagnosis of clinical bacterial infection, effectively prompts the patient’s bacterial infection, and can be directly evaluated according to the PCT value of the patient’s condition and prognosis.