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作者用健康人外周血白细胞为滋养层的双层琼脂培养体系,观察了8例6～8周龄的人胚胎和14例15～27周龄胎儿的造血组织和淋巴组织中粒-巨噬细胞前体细胞(CFU-C)的含量。结果:6～8周龄人胚的肝脏已有78.6 CFU-C/10~5有核细胞。一直到22周时才逐渐下降,于第26～27周时,肝脏CFU-C实际上完全消失。在人体子宫内发育期间,肝脏主要含红系统细胞。从10～11周开始,造血作用逐渐由肝脏转移到骨髓。胚胎和胎儿的肝脏主要是粒细胞生成的器官。骨髓中过氧化物酶阳性的细胞达8.2～21%,其余为红系和淋巴系细胞。14周的胚胎股骨即出现CFU-C,至22～23周逐渐增加,于24～25周达最高值(122.3CFU-C/10~5有核细胞)。26～27周时减少到56.2CFU-C/10~5有核细胞。脾脏于20周时出
The author used double-layer agar culture system of healthy human peripheral blood leukocytes as a trophoblast to observe the effect of granulocyte-macrophage in hematopoietic tissue and lymphoid tissue from 8 cases of 6-8 weeks old human embryos and 14 cases of 15-27 weeks fetuses Precursor cells (CFU-C) content. Results: There were 78.6 CFU-C / 10 ~ 5 nucleated cells in the liver of 6-8 week old human embryos. It did not decline until 22 weeks, and the CFU-C in the liver virtually disappeared from the 26th to the 27th week. During human uterine development, the liver contains predominantly red system cells. From 10 to 11 weeks, hematopoietic function gradually transferred from the liver to the bone marrow. The liver of embryos and fetuses is primarily an organ of granulocytes. Bone marrow peroxidase-positive cells reached 8.2 to 21%, the rest of the erythroid and lymphoid cells. Fourteen weeks of embryonic femur showed CFU-C, gradually increased from 22 to 23 weeks, reaching the highest value (122.3 CFU-C / 10 to 5 nucleated cells) from 24 to 25 weeks. From 26 to 27 weeks reduced to 56.2 CFU-C / 10 ~ 5 nucleated cells. Spleen at 20 weeks out