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应用蛇毒去纤酶治疗血栓性疾患,在国内尚无报道,我院首先使用中国科学院昆明动物研究所分离提纯的尖吻蝮蛇(Agkistrobon acutus)蛇毒去纤酶(简称去纤酶),对21例血栓性患者的临床疗效和血液凝固性能的作用,进行初步的观察,现报道如下:材料与方法 21例血栓性患者均排除出血倾向和过敏性体质:其中①冠心病12例,年龄48~63岁,男11例,女1例;其中急性心肌梗塞1例,陈旧性心肌梗塞2例。均有不同程度的心绞痛发作。②脑血管意外4例,年龄49~70岁,均为男性,其中2例为新近发生的脑血栓形成,1例为脑血栓形成后遗症,1例为脑动脉硬化症,脑供血不足。③视网
Application of snake venom defibrase treatment of thrombotic diseases, no reports in the country, our hospital first using the Kunming Institute of Zoology, Chinese Academy of Sciences isolated Agkistrobon acutus snake venom defibrase (referred to as defibrase), 21 Cases of thrombotic patients with clinical efficacy and blood coagulation, the initial observations are reported as follows: Materials and methods 21 cases of thrombotic patients were excluded bleeding tendency and allergic constitution: ① coronary heart disease in 12 cases, aged 48 ~ 63 years old, 11 males and 1 females; 1 case of acute myocardial infarction, 2 cases of old myocardial infarction. Have varying degrees of angina pectoris. ② Cerebrovascular accident in 4 cases, aged 49 to 70 years old, were men, including 2 cases of recent cerebral thrombosis, 1 case of cerebral thrombosis sequelae, 1 case of cerebral arteriosclerosis, cerebral insufficiency. ③ visual network