河南贲门癌高发区2196例贲门癌发生部位分析

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[目的]分析河南贲门癌高发区贲门癌发生部位及其相关病理因素的特点。[方法]据肿瘤与齿状线的关系将贲门癌分为6种类型:A型:肿瘤全部位于齿状线下方;B型:2/3位于齿状线下方;C型:1/2位于齿状线下方;D型:1/3位于齿状线下方;E型:全部位于齿状线上方;F型:齿状线完全被肿瘤侵犯,难以区分肿瘤与齿状线的关系。分析肿瘤分布部位与大体类型、TNM分期及分化程度的关系。[结果]男性和女性贲门癌发生部位均以A型和B型为主(>83%)。早期贲门癌96例(4.4%),主要为A型(95.8%),中晚期贲门癌主要为A型和B型(>83%);贲门癌大体类型,TNM分期及分化程度与其部位分布之间均显著性相关(P<0.01)。[结论]河南贲门癌高发区83%以上贲门癌发生于解剖学贲门部位,不同于西方国家食管/贲门交界部腺癌,提示中国人贲门癌应作为一种独立的疾病,且不同部位贲门癌具有不同的临床意义。 [Objective] To analyze the characteristics of the occurrence of cardiac cancer and its related pathological factors in the high incidence of cardiac cancer in Henan Province. [Methods] According to the relationship between tumor and dentate line, cardiac cancers were divided into 6 types: Type A: tumors were all located below the dentate line; Type B: 2/3 was located below the dentate line; Type C: 1/2 was located Below the dentate line; D-type: 1/3 below the dentate line; E-type: all located above the dentate line; F-type: dentate line is completely invaded by the tumor, it is difficult to distinguish the relationship between the tumor and the dentate line. The relationship between tumor distribution and gross type, TNM stage and differentiation degree was analyzed. [Results] The sites of cardiac cancer in males and females were mainly type A and type B (>83%). There were 96 cases (4.4%) of early cardiac cancers, mainly type A (95.8%), and mainly type A and type B (>83%) of advanced cardiac cancers; general types of cardia cancers, TNM stage, differentiation degree, and site distribution. There was significant correlation between the two groups (P<0.01). [Conclusion] More than 83% of cardiac cancer in high-risk areas of cardiac cancer occurred in cardiac anatomy, which is different from adenocarcinoma of esophageal/cardiac border in western countries. This suggests that Chinese cardia cancer should be treated as an independent disease and have different cardiac cancers. Has a different clinical significance.
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