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目的:探讨应用米非司酮联合米索前列醇及雌激素在稽留流产中的临床效果。方法:选取稽留流产患者64例作为研究对象。随机分成观察组和对照组,各32例。观察组采用米非司酮联合米索前列醇及戊酸雌二醇治疗稽留流产;对照组服用戊酸雌二醇片治疗。两组均采用相同的清宫术。对两组患者的平均出血量、平均手术时间、治疗效果作对比分析。结果:观察组患者行清宫术的平均手术时间、出血量、1次清宫成功率较对照组均具有优势,P<0.05;观察组总有效率明显高于对照组,P<0.05。结论:应用米非司酮联合米索前列醇及戊酸雌二醇治疗女性稽留流产患者具有出血量低、安全、疗效好的优点,具有推广价值。
Objective: To investigate the clinical effect of mifepristone combined with misoprostol and estrogen in missed abortion. Methods: 64 missed abortion patients were selected as the research object. Randomly divided into observation group and control group, 32 cases in each. The observation group used mifepristone combined with misoprostol and estradiol valerate in the treatment of missed abortion; the control group was treated with estradiol valerate tablets. Both groups used the same curettage. The average amount of bleeding, the average operation time, the therapeutic effect of two groups of patients for comparative analysis. Results: The average operation time, bleeding volume and success rate of one curettage in observation group were superior to those in control group (P <0.05). The total effective rate in observation group was significantly higher than that in control group (P <0.05). Conclusion: The application of mifepristone combined with misoprostol and estradiol valerate in female patients with missed abortion has the advantages of low bleeding, safe and good curative effect, and has the promotion value.