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目的 :通过观察高强度聚焦超声 (HIFU)治疗Ⅰ、Ⅱ期乳癌块的影像和病理变化情况 ,探讨HIFU治疗乳腺癌的临床疗效。方法 :海扶超声聚焦刀治疗Ⅰ、Ⅱ期乳腺癌 18例 ,HIFU术后辅以放化疗和内分泌治疗。结果 :经HIFU治疗 18例Ⅰ、Ⅱ期乳腺癌后 3～ 2 6个月随访的超声影像观察 ,癌块逐渐缩小 ,最后完全消失 ;病理穿刺证实癌细胞蜕变坏死。结论 :HIFU保乳治疗乳腺癌的初步临床疗效是肯定的 ,高强度聚焦超声保乳术可能成为乳腺癌保乳治疗的主要方法之一
Objective: To observe the imaging and pathological changes of stage Ⅰ and stage Ⅱ breast cancer by observing high intensity focused ultrasound (HIFU) and to explore the clinical effect of HIFU in the treatment of breast cancer. Methods: Haifu ultrasound focused knife treatment of Ⅰ, Ⅱ breast cancer in 18 cases, HIFU supplemented with radiotherapy and chemotherapy and endocrine therapy. Results: Ultrasound imaging of 18 cases of stage I and II breast cancer after HIFU treatment for 3 to 26 months showed that the tumor mass gradually decreased and finally disappeared. Pathological examination confirmed the necrosis of cancer cells. Conclusion: The preliminary clinical efficacy of HIFU breast-conserving treatment of breast cancer is affirmed, high-intensity focused ultrasonic breast-conserving surgery may become one of the main methods of breast-conserving treatment of breast cancer