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目的观察表阿霉素联合奥沙利铂及氟尿嘧啶治疗晚期胃癌的临床疗效观察及不良反应,用于指导临床用药。方法选择胃癌晚期患者108例,随机分成对照组和治疗组各54例,其中治疗组用表阿霉素、奥沙利铂、氟尿嘧啶联合治疗,与对照组用替吉奥胶囊治疗进行疗效比较观察。结果治疗组完全缓解35例,总有效率92.59%;对照组完全缓解14例,总有效率44.44%。治疗组疗效明显优于对照组。结论表阿霉素、奥沙利铂及氟尿嘧啶联合治疗晚期胃癌临床疗效优于替吉奥胶囊的治疗,且能缩短疗效,降低复发率,值得临床推广应用。
Objective To observe the clinical efficacy and adverse reactions of epirubicin combined with oxaliplatin and fluorouracil in the treatment of advanced gastric cancer and to guide clinical medication. Methods One hundred and eighty patients with advanced gastric cancer were randomly divided into control group and treatment group (n = 54). The treatment group was treated with epirubicin, oxaliplatin and fluorouracil, compared with the control group . Results In the treatment group, 35 cases were completely relieved, with a total effective rate of 92.59%. In the control group, 14 cases were completely relieved, with a total effective rate of 44.44%. The treatment group was significantly better than the control group. Conclusion Epirubicin, oxaliplatin and fluorouracil combined treatment of advanced gastric cancer clinical efficacy is better than for the treatment of Capsules, and can shorten the curative effect and reduce the recurrence rate, worthy of clinical application.