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目的:对早产胎膜早破的危险因素、不同孕周的临床处理方式以及对妊娠结局产生的影响进行探讨分析。方法:回顾性分析327例PPROM发生的原因、临床处理方式及对母婴的影响,并对孕28-33+6周、34-36+6周两组作分析比较。结果:两组孕妇中,分娩方式对母儿的影响差异无统计学意义(P>0.05)。孕28-33+6周PPROM发生围产儿死亡率、各种并发症发病率明显高于34-36+6周者(P<0.05)。结论:对于发生PPROM的孕妇,孕周为28-33+6周者宜采用期待疗法,尽可能延长孕周,同时采取促胎儿肺成熟治疗和预防感染治疗,能够有效降低新生儿并发症发生率,有效提高新生儿存活率。
Objective: To explore the risk factors of preterm premature rupture of membranes, the clinical treatment of different gestation weeks and the impact on pregnancy outcomes. Methods: Retrospective analysis of 327 cases of PPROM causes, clinical management and the impact of maternal and infant, and pregnant 28-33 +6 weeks, 34-36 +6 weeks for analysis and comparison. Results: In the two groups of pregnant women, the mode of delivery had no significant difference on maternal and childbirth (P> 0.05). The perinatal mortality rate in PPROM at 28-33 + 6 weeks pregnant was significantly higher than that in 34-36 + 6 weeks (P <0.05). Conclusions: Pregnancy women with PPROM should be treated with expectant therapy at gestational weeks 28-33 + 6 weeks to prolong gestational age as much as possible and to promote fetal lung maturation and prevention of infection, which can effectively reduce the incidence of neonatal complications , Effectively improve the survival rate of newborns.