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目的:分析临床子宫内膜癌的病理特点。方法:回顾性分析39例子宫内膜癌患者的临床资料,另选同期的52例子宫内膜增厚患者的临床资料;对比两组患者的临床资料,并进行多因素回归分析。结果:子宫内膜癌组与子宫内膜增厚组的子宫内膜厚度≥10mm、绝经年龄≥55岁、合并阴道出血或排出粘液、合并高血压的比例均具有显著性差异(P<0.05);多因素回归分析:子宫内膜厚度≥10mm、绝经年龄≥55岁、阴道出血或排出粘液、高血压与子宫内膜癌风险呈正相关(P<0.05);绝经年限、生育史与子宫内膜癌风险呈负相关(P<0.05)。结论:子宫内膜癌的病理与子宫内膜增厚密切相关,子宫内膜增厚作为子宫内膜癌发生的独立危险因素,结合子宫内膜厚度≥10mm、绝经年龄≥55岁,合并阴道出血或排出粘液、高血压等危险因素,可进一步增大子宫内膜癌发生的风险。
Objective: To analyze the pathological features of clinical endometrial cancer. Methods: The clinical data of 39 patients with endometrial carcinoma were retrospectively analyzed. The clinical data of 52 patients with endometrial thickening were selected. The clinical data of two groups of patients were compared and analyzed by multivariate regression analysis. Results: The endometrial cancer group and endometrial thickening group had a significant difference in endometrial thickness ≥10 mm, menopausal age ≥55 years, combined with vaginal bleeding or mucus excretion, and hypertension (P <0.05) ; Multivariate regression analysis: endometrial thickness ≥ 10mm, menopausal age ≥ 55 years old, vaginal bleeding or mucus excretion, hypertension and the risk of endometrial cancer was positively correlated (P <0.05); menopause, birth history and endometrial Cancer risk was negatively correlated (P <0.05). Conclusion: The pathology of endometrial carcinoma is closely related to the thickening of endometrium. Endometrial thickening is an independent risk factor for endometrial cancer. Combined with endometrial thickness ≥10mm and menopausal age ≥55 years old, combined with vaginal bleeding Or discharge mucus, hypertension and other risk factors, can further increase the risk of endometrial cancer.