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目的 :观察杏丁注射液治疗急性脑梗死的疗效。方法 :将入选患者按入院顺序随机分为杏丁注射液治疗组和复方丹参对照组 ,于d1,3,7,15分别进行神经功能缺损、临床疗效全面观察及治疗前后血液流变学相关指标、脑电功率谱、脑血流检测。结果 :治疗组全血粘度、血浆粘度、血小板聚集率、红细胞压积、红细胞电泳时间及脑电功率谱和脑血流均明显改善 ,与对照组相比有显著差异 ;治疗组有效率和总进步率都显著高于对照组 ;2组均无明显不良反应。结论 :杏丁注射液可作为急性脑梗死早期的治疗药物。
Objective: To observe the effect of Xingding injection on acute cerebral infarction. Methods: The patients were randomly divided into Xingdin injection group and Salvia miltiorrhiza control group according to the order of hospital admission. Neurological deficits were performed on d1, 3, 7, and 15 respectively. The clinical curative effect was comprehensively observed and the indexes of hemorheology before and after treatment , EEG power spectrum, cerebral blood flow detection. Results: The whole blood viscosity, plasma viscosity, platelet aggregation rate, hematocrit, erythrocyte electrophoresis time, EEG power spectrum and cerebral blood flow in the treatment group were significantly improved compared with the control group; the treatment group efficiency and overall progress Rates were significantly higher than the control group; 2 groups were no significant adverse reactions. Conclusion: Xingding injection can be used as early treatment of acute cerebral infarction drugs.