几乎每年冬季均有流感病毒流行,A型或B型发病率高达40％,并持续6周以上。特别是发达国家,65岁以上老人80％～90％因流感而死亡。作者报道在流感季节,老年人中使用MF-59佐剂流感疫苗的安全性和免疫原性,并与无佐剂疫苗作比较。 Influenza viruses are endemic in almost every winter, with a 40% incidence of type A or B disease and persisting for more than 6 weeks. Especially in developed countries, 80% to 90% of people over the age of 65 die of flu. The authors report the safety and immunogenicity of the MF-59 adjuvanted influenza vaccine in the elderly during the flu season and compared it to the unadjuvanted vaccine.