烯醇化酶是生物体中广泛存在的一种重要的糖酵解酶类,近来发现其还具有激活纤溶酶原的功能,参与寄生虫在宿主体内侵染和转移过程,并能下调宿主免疫功能,协助寄生虫逃避宿主的免疫攻击。本文总结当前对寄生虫烯醇化酶的研究进展,旨在探究其用于寄生虫病诊断、药物研发及疫苗靶标的可能性。 Enolase is an important glycolytic enzyme that exists widely in organisms and has recently been found to activate Plasminogen, participate in the infection and metastasis of parasites in the host, and can down-regulate host immunity Function to help parasites evade the host’s immune attack. This article summarizes the current research progress on parasite enolase aimed at exploring its potential for diagnosis of parasitic diseases, drug development and vaccine targets.