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有机磷农药是一类使用广泛的杀虫剂,在许多食物中均能检测到其残留。不同的有机磷农药同时进入人体的靶器官后,就会产生相同的毒效应,共同对乙酰胆碱酯酶的活性抑制。因此,对有机磷农药的累积暴露进行风险评估显得格外重要。阐述了目前我国有机磷农药污染现状及其联合作用对机体的危害,同时也详细介绍了国内外对有机磷农药累积暴露风险评估的研究现状。
Organophosphorus pesticides, a widely used class of pesticides, detect their residues in many foods. Different organophosphorus pesticides into the target organ of the human body at the same time, will have the same toxic effect, together inhibit the activity of acetylcholinesterase. Therefore, the risk assessment of cumulative exposure to organophosphorus pesticides is of particular importance. The present situation of organophosphorus pesticide contamination in our country and the harmful effects of the combined action on the organism are also described. Meanwhile, the current research status of the cumulative risk assessment of organophosphorus pesticides in China and abroad is also introduced in detail.