观察TTV(Transfusiontransmittedvirus,TTV)阳性肝病患者的临床特征。用巢式PCR法检测血清TTVD NA ,同时观察血清生化指标和肝组织学的变化。TTV感染者的血清学模式以HBV、HCV、HAV、HEV混合感染为主 ,占 6 1.1% ( 2 2 /36 ) ,临床表现以乏力、纳差为特征 ,TBL、ALT变化不明显 ;而TTV单独感染者为 38.9% ( 14/36 )临床特征与急性黄疸性肝炎相似。TTV可与各型已知肝炎病毒混合感染 ,可呈隐匿性发病。 To observe the clinical features of patients with TTV positive liver disease. The serum TTVD NA was detected by nested PCR, and the changes of serum biochemical indexes and liver histology were also observed. The serological patterns of TTV infection were mainly HBV, HCV, HAV and HEV, accounting for 61.1% (2/36) of patients with TTV infection. The clinical manifestations were characterized by fatigue and anorexia, while the changes of TBL and ALT were insignificant. TTV Individual infections were 38.9% (14/36) with clinical features similar to acute jaundice hepatitis. TTV can be mixed with various types of known hepatitis virus infection, can be occult onset.