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背景:脂蛋白相关性磷脂酶A2(Lp-PLA2)是一种新型标记物,参与了血管炎症。炎症亦与冠状动脉粥样硬化相关。检验如下假设:冠状动脉局部的Lp-PLA2产量在早期冠状动脉粥样硬化患者中增强,且与局部内皮功能相关。方法和结果:纳入15例轻度冠状动脉粥样
Background: Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a novel marker involved in vascular inflammation. Inflammation is also associated with coronary atherosclerosis. The hypothesis was tested that Lp-PLA2 production in the coronary arteries is enhanced in patients with early-stage coronary atherosclerosis and is associated with local endothelial function. Methods and Results: Fifteen patients with mild coronary atherosclerosis were enrolled