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目的评价血浆D-二聚体在监测肾病综合征患者高凝和纤溶状态的应用价值。方法采用免疫比浊试验,检测43例肾病综合征患者及35例正常健康对照者血浆中D-二聚体的含量。结果所测肾病综合征患者血浆中D-二聚体的含量均比正常对照组中健康者有显著升高。结论血浆中D-二聚体的含量可作为观察肾病综合征患者高凝和纤溶状态的指标,对临床治疗具有重要价值。
Objective To evaluate the value of plasma D-dimer in monitoring hypercoagulability and fibrinolysis in patients with nephrotic syndrome. Methods Immunoturbidimetric assay was used to detect plasma D-dimer levels in 43 patients with nephrotic syndrome and 35 healthy controls. Results The plasma levels of D-dimer in patients with nephrotic syndrome were significantly higher than those in healthy controls. Conclusion The content of D-dimer in plasma can be used as an index to observe the hypercoagulability and fibrinolytic status in patients with nephrotic syndrome, which is of great value for clinical treatment.