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目的探讨尿路感染病原菌的分布及耐药性特征,为临床合理选用抗生素提供依据。方法收集183例尿路感染患者中段尿标本分离的病原菌进行鉴定及药敏试验。结果尿路感染中革兰氏阴性菌感染占总体的68.9%,大肠埃希氏菌占53.0%,革兰氏阳性菌中,肠球菌占19.6%,葡萄球菌占10.9%,药敏显示,革兰氏阴性菌对亚胺增南敏感性最高、其次是呋喃妥因、阿米卡星。革兰氏阳性菌对抗菌素的敏感性以替考拉宁、万古霉素最高。结论尿路感染应及时进行尿液细菌培养及药敏试验,慎重应用抗生素,以减少耐药菌的产生。
Objective To investigate the distribution and drug resistance characteristics of pathogenic bacteria in urinary tract infection and provide the basis for rational use of antibiotics in clinic. Methods The pathogenic bacteria isolated from urine samples of 183 cases of urinary tract infection were collected and identified. Results Urinary tract infection accounted for 68.9% of Gram-negative bacteria, Escherichia coli accounted for 53.0%, gram-positive bacteria, enterococci accounted for 19.6%, Staphylococcus accounted for 10.9%, drug sensitivity showed that leather Negative susceptibility to N. meningitidis was the highest in N. l blue, followed by nitrofurantoin and amikacin. Gram-positive bacteria on antibiotic sensitivity to teicoplanin, vancomycin highest. Conclusions Urinary tract infection should be promptly tested for bacterial culture and susceptibility testing of urine. Antibiotics should be used prudently to reduce the production of resistant bacteria.