Preparation of Elemental Tellurium Nanoparticles-Sucrose Sol and Its Antioxidant Activity in Vitro

来源 :Journal of Wuhan University of Technology(Materials Science | 被引量 : 0次 | 上传用户:A578964735
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The elemental tellurium nanoparticles(TeNPs)-sucrose sol was prepared by the reaction of sodium tellurite with ascorbic acid in sucrose aqueous solution.The results indicated that TeNPs were dispersion excellent in the TeNPs-sucrose sol and the morphology of TeNPs was needle-like with about 70 nm in width and 500 nm in length.The antioxidant activity of the TeNPs-sucrose sol in vitro was estimated by pyrogallol autoxidation method,Fenton method and oxygen radical absorbance capacity(ORAC) assay.The results showed that a certain amount of TeNPs-sucrose sol could effectively scavenge superoxide anion free radical and hydroxyl free radical with scavenging rates of 73 % and 57 %,respectively.ORAC assay was used to measure the total antioxidant capacity of TeNPs-sucrose sol.The order of ORAC values was 2.25 μmol·L-1 TeNPs-0.025 % sucrose sol > 0.025 % sucrose > 2.25 μmol·L-1Na 2 TeO 3 > 1.63 μmol·L-1ascorbic acid.The results suggested that the TeNPs-sucrose sol had the excellent antioxidant activity and TeNPs were the dominating contributors to antioxidant capacity of the TeNPs-sucrose sol. The elemental tellurium nanoparticles (TeNPs) -sucrose sol was prepared by the reaction of sodium tellurite with ascorbic acid in sucrose aqueous solution. These results indicated that TeNPs were dispersion excellent in the TeNPs-sucrose sol and the morphology of TeNPs was needle-like with about 70 nm in width and 500 nm in length. antioxidant activity of the TeNPs-sucrose sol in vitro was estimated by pyrogallol autoxidation method, Fenton method and oxygen radical absorbance capacity (ORAC) assay. The results showed that a certain amount of TeNPs -sucrose sol could scavenge superoxide anion free radical and hydroxyl free radical with scavenging rates of 73% and 57% respectively. ORAC assay was used to measure the total antioxidant capacity of TeNPs-sucrose sol. the order of ORAC values ​​was 2.25 μmol · L-1 TeNPs-0.025% sucrose sol> 0.025% sucrose> 2.25 μmol·L-1Na 2 TeO 3> 1.63 μmol·L-1 ascorbic acid.The results suggested that the TeNPs-sucrose sol had the excellent antio xidant activity and TeNPs were the dominating contributors to antioxidant capacity of the TeNPs-sucrose sol.
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