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目的探讨首次脑梗死患者血清同型半胱氨酸(Hcy)含量与脑梗死发生的关系。方法收集2012年1月至2013年10月首次发病的72例急性脑梗死患者,其中动脉硬化性血栓形成性脑梗死(ACI)38例,腔隙性脑梗死(LI)24例,脑栓塞(CE)10例,收集同期健康体检者(对照组)50例,测定血清Hcy含量。结果 ACI组、LI组及CE组血清Hcy含量明显高于对照组(P<0.01);三组间血清Hcy含量比较差异未见统计学意义(P>0.05)。结论急性脑梗死患者Hcy含量明显增高。观察Hcy水平的改变对于预测脑梗死的发生有意义。
Objective To investigate the relationship between serum homocysteine (Hcy) and the occurrence of cerebral infarction in patients with first cerebral infarction. Methods Seventy-two patients with acute cerebral infarction were collected from January 2012 to October 2013. Among them, 38 cases were atherosclerotic thrombotic cerebral infarction (ACI), 24 cases were lacunar infarction (LI), 24 cases were cerebral embolism CE) 10 cases, collect the same period of health examination (control group) 50 cases, determination of serum Hcy levels. Results Serum Hcy levels in ACI group, LI group and CE group were significantly higher than those in control group (P <0.01). There was no significant difference in serum Hcy levels between the three groups (P> 0.05). Conclusion Hcy in patients with acute cerebral infarction was significantly higher. Observe that the change of Hcy level is significant to predict the occurrence of cerebral infarction.