慢肝合剂促进大鼠肝细胞再生实验研究

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目的观察慢肝合剂对肝细胞再生作用的影响。方法采用大鼠部分肝切除法复制肝细胞再生模型,给予慢肝合剂,并与促肝细胞生长因子治疗者对比,同时计算肝指数的变化,采用光镜观察肝脏HE的变化及用电镜观察肝脏超微结构的变化。结果中药组肝指数、肝脏HE及超微结构的改善情况明显优于模型组。结论慢肝合剂有明显的促进肝细胞再生的作用。 Objective To observe the effect of slow liver mixture on hepatocyte regeneration. Methods Rat hepatectomy was used to duplicate the hepatocyte regeneration model. Slow liver mixture was given and compared with hepatocyte growth factor treatment. The changes of hepatic index were calculated. The changes of hepatic HE were observed by light microscope and the liver was observed by electron microscope. Ultrastructural changes. Results The improvement of hepatic index, hepatic HE and ultrastructure of traditional Chinese medicine group was obviously better than that of model group. Conclusion Slow liver mixture can obviously promote the regeneration of hepatocytes.
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