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目的探讨孕晚期血清游离雌三醇(E3)测定对早产评估的价值。方法对561例产妇在孕晩期后采用化学发光法测定血清E3,跟踪随访产妇生产状况。结果早产孕妇平均E3为(12.29±5.94)ng/ml,明显低于足月产孕妇的(18.85±6.77)ng/ml(P<0.01);血清E3含量偏低组孕妇早产率为15.3%,明显高于雌三醇正常组的4.1%和雌三醇偏高组的1.1%(P<0.01)。结论孕晚期孕妇血清E3含量偏低者容易发生早产。
Objective To investigate the value of serum free estriol (E3) determination in preterm third trimester of pregnancy. Methods 561 pregnant women were tested for serum E3 by chemiluminescence after the pregnant period, and follow-up maternal production was followed up. Results The average preterm birth E3 was (12.29 ± 5.94) ng / ml, which was significantly lower than that of full term pregnant women (18.85 ± 6.77) ng / ml (P <0.01). The premature birth rate of pregnant women with low E3 level was 15.3% Significantly higher than 4.1% of the normal estriol group and 1.1% of the estriol high group (P <0.01). Conclusion Pregnant women with low serum E3 in late pregnancy are prone to preterm birth.