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It is one of the important fields so far to in vestigate the effects of hematopoietic stromal cell on hematopoietic reconstitut ion. There are six problems in this field: ①The classification, characteristi cs and origin of stromal cells; ②The mechanisms of constitution for stromal cel ls in marrow hematopoietic inductive microenvironment; ③The proliferation and d ifferentiation of hematopoietic cell are supported by stromal cell; ④The bone m arrow hematopoietic reconstitution by marrow stromal cells transplantation; ⑤Th e hematopoietic function effected by abnormal marrow stromal cells; ⑥Unconventi onality of bone marrow hematopoietic inductive microenvironment in states of som e diseases etc. The related different points of views and some problems in this field are also discussed.
It is one of the important fields so far to in vestigate the effects of hematopoietic stromal cell on hematopoietic reconstitut ion. There are six problems in this field: ①The classification, characteristi cs and origin of stromal cells; ②The mechanisms of constitution for stromal cel ls in marrow hematopoietic inductive microenvironment; ③ The proliferation and d differentiation of hematopoietic cells are supported by stromal cells; ④ The bone m arrow hematopoietic reconstitution by marrow stromal cells transplantation; ⑤ Th e hematopoietic function effected by abnormal marrow stromal cells; ⑥ Unconventi onality of bone marrow hematopoietic inductive microenvironment in states of som e diseases etc. The related different points of views and some problems in this field are also discussed.